Opioid receptor types on adrenergic nerve terminals of rabbit ear artery
نویسندگان
چکیده
منابع مشابه
Biphasic vasoconstriction of the rabbit ear artery.
Sympathetic nerve stimulation and intralummal norepinephrine infusion for more than 15 seconds produced a biphasic response in the isolated rabbit ear artery perfused with RREBS solution. This response consisted of an initial rapid constriction (phase A), which was followed by partial relaxation, and a final slowly developing constriction (phase B), which lasted for the duration of nerve stimul...
متن کاملComparison of constrictor responses of the rabbit ear artery to norepinephrine and to sympathetic nerve stimulation.
The perfused isolated rabbit ear artery was used as a vascular model to compare the constrictor responses to exogenous and endogenous norepinephrine. The aim of the study was to estimate the concentrations of norepinephrine reaching the smooth muscle of the artery during sympathetic nerve stimulation. The artery was perfused so that exogenous norepinephrine was introduced exclusively from the a...
متن کاملComparison of Constrictor Responses of the Rabbit Ear Artery to Noreplnephrine and to Sympathetic Nerve Stimulation
The perfused isolated rabbit ear artery was used as a vascular model to compare the constrictor responses to exogenous and endogenous norepinephrine. The aim of the study was to estimate the concentrations of norepinephrine reaching the smooth muscle of the artery during sympathetic nerve stimulation. The artery was perfused so that exogenous norepinephrine was introduced exclusively from the a...
متن کاملKappa-opioid receptor activation modulates Ca2+ currents and secretion in isolated neuroendocrine nerve terminals.
Whole-cell patch-clamp recordings were performed together with time-resolved measurements of membrane capacitance (Cm) in nerve terminals acutely dissociated from neurohypophysis of adult rats to investigate modulation of Ca2+ currents and secretion by activation of opioid receptors. Bath superfusion of the kappa-opioid agonists U69,593 (0.3-1 microM), dynorphin A (1 microM), or U50,488H (1-3 m...
متن کاملInteraction between Antagonist of Cannabinoid Receptor and Antagonist of Adrenergic Receptor on Anxiety in Male Rat
Introduction: Anxiety is among the most common and treatable mental disorders. Adrenergic and cannabinoid systems have an important role in the neurobiology of anxiety. The elevated plus-maze (EPM) has broadly been used to investigate anxiolytic and anxiogenic compounds. The present study investigated the effects of intraperitoneal (IP) injection of cannabinoid CB1 receptor antagonist (AM251) i...
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ژورنال
عنوان ژورنال: British Journal of Pharmacology
سال: 1985
ISSN: 0007-1188
DOI: 10.1111/j.1476-5381.1985.tb08929.x